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What is Z-DNA?

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• This form of DNA gets its name from the zigzag orientation of its

sugar- phosphate backbone. (In contrast, B-DNA sugar-phosphate

backbone follows a regular path). It shows left handed coiling and has

12 base pairs per turn.

• Further, deoxyribose molecules have an alternating orientation so

that the repeating unit is a dinucleotide (compare with B-DNA, where

the repeating unit is a mononucleotide). Thus the 12 base pairs per

turn of the Z-DNA form 6 dinucleotide pairs.

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